Ingredient guide

Sodium hyaluronate: what the evidence says, and can you get it from food?

The dose in the tub is exactly the dose used in the trials — 120 mg, repeatedly, across multiple placebo-controlled studies. That's rarer than it should be.

Blueprint dose120 mg
Typical supplement dose120 mg
From food?Not practical
The short answer

No realistic food route at anything like 120 mg.

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Can you get it from food?

Your body makes hyaluronic acid; it isn't a nutrient you're meant to eat. Dietary sources are limited to animal connective tissue, skin and cartilage — chicken skin, bone broth, certain organ meats — in amounts that are small, poorly characterised and highly variable between samples. Nobody has established a per-serve figure worth quoting, and we're not going to invent one. If 120 mg is the target, a supplement is the only way there.

FoodTo match the dose
Chicken skin and cartilageNot quantifiable from available dataContains HA; amounts poorly characterised
Bone brothSmall and highly variableDepends on preparation
Organ meatsSmallNot a practical route to 120 mg

Dietary sources are animal-derived, though most supplemental hyaluronic acid is produced by bacterial fermentation and is suitable for vegetarians — worth checking the label.

What the research actually shows

Unusually tidy alignment between the research and the product. Multiple randomised, double-blind, placebo-controlled trials have used 120 mg per day for 12 weeks. One in 40 healthy adults reported improvements in wrinkle assessment, stratum corneum water content, transepidermal water loss and skin elasticity versus placebo. Another in 50 Japanese men and women reported reduced wrinkle volume ratio from eight weeks. A more recent trial randomised 150 participants across 60 mg/day, 120 mg/day and placebo for 12 weeks — a dose-comparison design that's more informative than a single-dose trial.

On certainty: Two caveats worth keeping in view. These are modest sample sizes, and skin-appearance endpoints are harder to measure objectively than something like sleep latency. Encouragingly, the trials use instrument-based measures (corneometry, transepidermal water loss) rather than relying on self-report alone.

The studies referenced

This article is general information, not medical advice, and nothing in it is a recommendation to take anything. Supplements are not a substitute for a varied diet. Talk to your GP or pharmacist before starting any supplement — particularly if you're pregnant or breastfeeding, taking medication, or managing a health condition.